Documentation#
pyrovelocity
is a Bayesian, generative, and multivariate RNA velocity
model to estimate uncertainty in predictions of future cell states from
minimal models approximating splicing dynamics.
This approach models raw sequencing counts with synchronized cell time across
all expressed genes to provide quantifiable information on
cell fate choice and developmental trajectory dynamics.
Features#
Probabilistic modeling of RNA velocity
Direct modeling of raw spliced and unspliced read counts
Diagnostic analyses and visualizations of model uncertainty
Synchronized cell time estimation across genes
Multivariate modeling of gene expression and velocity prediction